how far does the eye of the Xanathar thieves guild spread across Faerun? My players managed to earn the wrath of Xanathar himself and I’m wondering where is safe: Athkatla? Thay? Or is it confined mainly to Waterdeep and surrounding areas? Well, there's safe and then there's safe.
Let's just say MOSTLY confined to the Deep and environs.
Both places you mention have their own crime lords who fend off the Xanathar's agents VERY effectively.
There's a real-world saying about frying pans and fires…#Realmslore

— Ed Greenwood (@TheEdVerse) November 29, 2021

Thanks heaps! So they may have to watch their backs in Neverwinter or Baldur’s Gate? Oh, yes. That's not to stay that those places don't have their own crime lords, who may deliberately thwart the Xanathar's agents even if they're not certain precisely what they're thwarting, but the agents DO exist.#Realmslore

— Ed Greenwood (@TheEdVerse) November 29, 2021